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Place of Origin :	China, Enticavir
Brand Name :	World Caring, active pharmaceutical ingredient
Certification :	COA
Model Number :	C-045
MOQ :	1g
Price :	negotiable
Packaging Details :	Aluminum Foil Bag for 1kg, 25kg per fiber drum
Delivery Time :	7days
Payment Terms :	T/T, Western Union, Paypal
Supply Ability :	5000kgs per month
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Active Pharmaceutical Ingredient 99% purity Enticavir /CAS

142217-69-4

Specifications:

Name:Enticavir

Synonyms : 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one

Molecular Formula : C12H15N5O3

Molecular Weight : 277.28
CAS:142217-69-4

Uses:

Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir is a nucleoside analog (more specifically, aguanosine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. The drug's manufacturer claims that entecavir is more efficacious than previous agents used to treat hepatitis B (lamivudine and adefovir). It also helps prevent the hepatitis B virus from multiplying and infecting new liver cells. Entecavir is also indicated for the treatment of chronic hepatitis B in adults with HIV/AIDS infection.

Certificate of Analysis

Items	Specifications
[Description ]	It should be white or whitish crystalline powder, odorless and tasteless, very slightly in water, slightly soluble in methanol and insoluble in ether.
Specific rotation	Should be between +24°~+28°
[Identification]
(1) HPLC	Retention time of the principal peak obtained from the test solution should be identical with that of the reference solution.
(2) IR	IR spectrum of samples should be identical with that of the reference standard.
[Test]
pH	Should be between 5.5~7.5
Related substances
(1)Total impurity	Should be 0.3%max
(2)maximum single impurity	Should be 0.1%max
Enantiomer	Should be 0.2%max
Methanol	Should be 0.3%max
Dichloromethane	Should be 0.06%max
N- hexane	Should be 0.029%max
Tetrahydrofuran	Should be 0.072%max
N,N-dimethylformamide	Should be 0.088%max
Toluene	Should be 0.089%max
Water	Should be between 5.8%~6.5%
Residue on ignition	Should be 0.1%max
Heavy metal	Should be 20ppmmax
Assay	98.0%~102.0%(C12H15N5O3) calculated on anhydrous basis

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