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Place of Origin :	China， Rutin
Certification :	COA
Brand Name :	World Caring,herbal ingredient
MOQ :	1kg
Price :	Negotiable
Packaging Details :	Aluminum Foil Bag for 1kg, 25kg per fiber drum
Delivery Time :	3-5 days after payment is confirmed
Payment Terms :	T/T, Western Union, Paypal
Supply Ability :	5000kgs per month
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High quality Herbal Ingredient Rutin EP/NF11/DAB Version with EDMF

1.Sources and Habitation of Rutin

Rutin also called rutoside, quercetin-3-O rutinoside and sophorin, is the glycoside between the flavonol quercetin and the disaccharide rutinose, is extracted from the buds of Sophora japonica L.

Rutin is belonging to vitamin drugs, has effection of reducing capillary permeability and the role of brittleness, maintenaining and restoring the normal elasticity of the capillaries. Rutin can used for prevention and treatment of hypertensive cerebral hemorrhage, also used for food antioxidant and pigment.

2, Descriptions and Specifications of Rutin

Specifications: EP/NF11/DAB Version with EDMF Available

Molecular Formula: C₂₇H₃₀O₁₆

Molecular Mass: 610.52

CAS No.: 153-18-4

Constitutional Formula:

Certificate of Analysis:

Characters	Specifications	Results
Appearance	Yellow or greenish-yellow, crystalline powder	Greenish-yellow crystalline powder
Solubility	Practically insoluble in chloroform and ether	Complies
	Infinitesimally soluble in cool water	Complies
	Sparingly soluble in boiling ethanol and boiling water	Complies
	Dissolves in solution of alkali hydroxides	Complies
Identification	A.B.C	Complies
Tests
Loss on drying	5.5-9.0%	8.11%
Residue on Ignition	≤0.5%	0.32%
Red pigments	≤0.004%	Complies
Impurity quercetin	≤5%	3.6%
Heavy Metal	≤10ppm	8.4ppm
Mesh Size	100% pass 80 mesh	Complies
Assay (anhydrous substance)	≥95% by UV	98.54%
Microbiological test
Total plate count	≤1000CFU/g	Complies
Yeast & Mould	≤100CFU/g	Complies
E .Coli	Absent	Absent
Pseudomonas aeruginosa	Absent	Absent
Conclusion: the test results conform to NF11

Main Functions of Rutin:

1. Rutin inhibits platelet aggregation, as well as decreasing capillary permeability, making the blood thinner and improving circulation.

2. Rutin has anti-inflammatory activity.

3. Rutin inhibits aldose reductase activity. Aldose reductase is an enzyme normally present in the eye and elsewhere in the body. It helps change glucose into a sugar alcohol called sorbitol.

4. Rutin also strengthens the capillaries, and, therefore, can reduce the symptoms of haemophilia. It also may help to prevent a common unpleasant-looking venous edema of the legs. Rutin, as ferulic acid, can reduce the cytotoxicity of oxidized LDL cholesterol and lower the risk of heart disease.

5. There is also some evidence that Rutin can be used to treat hemorrhoids, varicosis, and microangiopathy.

6. Rutin is also an antioxidant, along with quercetin, acacetin, morin, hispidulin, hesperidin, and naringin; it was found to be the strongest.

7. Hydroxyethylrutosides, synthetic hydroxyethyl acetylations of rutin, are used in the treatment of chronic venous insufficiency.

Applications of Rutin:

(1)Rutin can be cooling bleeding, Liver Xiehuo, with anti-inflammatory effects

(2)Rutin with vitamin P-like effect, anti-viral

(3)Rutin also has a role in inhibiting aldose reductase

Safety Concerns of Rutin:

Rutin is LIKELY SAFE when used in food amounts and POSSIBLY SAFE when used appropriately in medicinal amounts for a short period of time.

It can cause some side effects including headache, flushing, rashes, or stomach upset.

Dosage Information of Rutin:

The recommended daily dose of rutin supplements is two 500-mg capsules/tablets per day.

Packaging & Delivery and Payments :

1• Packaging Detail: 1g/bag, 100g/bag,500g/bag,1kg/bag,25kg/drum.

2• Payment terms: T/T 100% in advance by Western union & Company bank account and Paypal(small sample only)

3• Payment way: We accept payments throught Telex transfer, Paypal, Western Union ....

4• Delivery Date:

a. Small order:3-3days,usually " in stock" orders can be dispatched in the same day once we get the payment);

b. Big order:5-15days,we will advise you ASAP, you can change the order or cancel the order ( full amount can be refund)

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High quality Herbal Ingredient Rutin EP/NF11/DAB Version with EDMF Images

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